27) Cobb, A. J. A.; Dell'Isola, A.; Abdulsattar, B. O.; McLachlan, M. M. W.; Neuman, B. W.; Müller, C.; Shankland, K.; Al-Mulla, H. M. N.; Binks, A. W. D.; Elvidge, W. Synthesis and antiviral activity of novel spirocyclic nucleosides.
26) Gadd, A. J. R.; Castelletto, V.; Kabova, E.; Shankland, K.; Perrie, Y.; Hamley, I.; Cobb, A. J. A.; Greco, F.; Edwards, A. D. High potency of lipid conjugated TLR7 agonist requires nanoparticulate or liposomal formulation.
25) Stendall, R. T.; Cobb, A. J. A. Syntheses and applications of enantiopure δ-amino acids and their precursors.
Tetrahedron, 2018, 74, 4917. Invited Article for the Barton Centennial Issue
24) Arezki, N. R.; Williams, A. C.; Cobb, A. J. A.; Brown, M. B. Design, synthesis and characterization of linear unnatural amino
acids for skin moisturization.
23) Al-Ani, W.; Shankland, K.; Cobb, A. J. A. Asymmetric Organocatalytic Synthesis of Cyclopentane γ-Nitroketones
Synlett, 2016, 27, 17. Steve Ley Symposium Issue
22) Bryant, L. A.; Fanelli, R.; Cobb, A. J. A. Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts.
21) Aitken, L. S.; Hammond, L. E.; Rajkumar, S.; Shankland, K.; Brown, G. D.; Cobb, A. J. A. Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to δ3-amino acids.
20) Gadd, A. J.; Greco, F.; Cobb, A. J. A.; Edwards, A. D. Targeted Activation of Toll-Like Receptors: Conjugation of a Toll-Like Receptor 7 Agonist to a Monoclonal Antibody Maintains Antigen Binding and Specificity.
19) Dell'Isola, A.; McLachlan, M. M. W.; Neuman, B. W.; Al-Mullah, H. M. N.; Binks, A. W. D.; Elvidge, W.; Shankland, K.; Cobb, A. J. A. Synthesis and Antiviral Properties of Spirocyclic [1,2,3]‐Triazolooxazine Nucleosides.
18) Aitken, L. S.; Arezki, N. R.; Dell'Isola, A.; Cobb, A. J. A. Asymmetric Organocatalysis and the Nitro Group Functionality.
17) Rajkumar, S.; Shankland, K.; Goodman, J. M.; Cobb, A. J. A. Organocatalytic Domino Reaction of Cyanosulfones: Access to Complex Cyclohexane Systems with Quaternary Carbon Centers.
16) Rangam, G.; Schmitz, K.-M.; Cobb, A. J. A.; Petersen-Mahrt, S. K. AID Enzymatic Activity Is Inversely Proportional to the Size of Cytosine C5 Orbital Cloud.
15) Shaikh, A.; Cobb, A. J. A.; Varvounis, G. Mild and Rapid Method for the Generation of ortho-(Naphtho)quinone Methide Intermediates
14) Rajkumar, S.; Shankland, K.; Brown, G. D.; Cobb, A. J. A. Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chem. Sci., 2012, 3, 584.
13) Fern, S. E.; Heath, P.; Cobb, A. J. A. Aldol reaction of butane-2,3-diacetal protected methyl glycerate.
12) Nodes, W. J.; Shankland, K.; Rajkumar, S.; Cobb, A. J. A. Asymmetric Phase-Transfer-Catalyzed Synthesis of Five-Membered Cyclic γ-Amino Acid Precursors.
11) Nodes, W. J.; Nutt, D. R.; Chippindale, A. M.; Cobb, A. J. A. Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters.
J. Am. Chem. Soc. 2009, 131, 16016.
10) Cobb, A. J. A. Recent highlights in modified oligonucleotide chemistry.
Org. Biomol. Chem. 2007, 5, 3260.
Publications from Pre-Independent Work
9) Kolstoe, S. E.; Mangione, P. P.; Bellotti, V.; Taylor, G. W.; Tennent, G. A.; Deroo, S.; Norrison, A. J.; Cobb, A. J. A.; Coyne, A.; McCammon, M. G.; Warner, T. D.; Mitchell, J.; Gill, R.; Smith, M. D.; Ley, S. V.; Robinson, C. V.; Wood, S. P.; Pepys, M. B. Proc. Natl. Acad. Sci. USA 2010, 107, 20483.
8) Pepys, M. B.; Hirschfield, G. M.; Tennent, G. A.; Gallimore, J. R.; Kahan, M. C.; Bellotti, V.; Hawkins, P. N.; Myers, R. M.; Smith, M. D.; Polara, A.; Cobb, A. J. A.; Ley, S. V.; Aquilina, J. A.; Robinson, C. V.; Sharif, I.; Gray, G. A.; Sabin, C. A.; Jenvey, M. C.; Kolstoe, S. E.; Thompson, D.; Wood, S. P. Nature 2006, 440, 1217.
7) Cobb, A. J. A.; Shaw, D. M.; Longbottom, D. A.; Gold, S. V.; Ley, S. V. Org. Biomol. Chem. 2005, 3, 84.
6) Mitchell, C. E. T.; Cobb, A. J. A.; Ley, S. V. Synlett 2005, 611.
5) Cobb, A. J. A.; Marson, C. M. Tetrahedron 2005, 61, 1269.
4) Cobb, A. J. A.; Longbottom, D. A.; Shaw, D. M.; Ley, S. V. Chem. Commun. 2004, 1808.
3) Cobb, A. J. A.; Shaw, D. M.; Ley, S. V. Synlett 2004, 558.
2) Marson, C. M.; Khan, A.; Porter, R. A.; Cobb, A. J. A. Tetrahedron Lett. 2002, 43, 6637.
1) Cobb, A. J. A.; Marson, C. M. Tetrahedron: Asymmetry 2001, 12, 1547.
Patents
Arezki, N.; Cobb, A.; Williams, A. C.; Brown, M. B. European Patent WO2014072747
Cobb, A. J. A.; Ley, S. V.; Pepys, M. B. European Patent WO03097104.