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    • Home
    • Andre
    • Research
    • Members
      • Current Members
      • Alumni
    • Photo Gallery
    • Publications
      • Publications 2020-present
      • Publications 2001-2019

The Cobb Research Lab

The Cobb Research LabThe Cobb Research LabThe Cobb Research Lab
  • Home
  • Andre
  • Research
  • Members
    • Current Members
    • Alumni
  • Photo Gallery
  • Publications
    • Publications 2020-present
    • Publications 2001-2019

PUBLICATIONS 2020-present

37) Varandas, P. A. M. M.; Belinha, R.; Cobb, A. J. A.; Ramalho, J. P. P.; Segundo, M. A.; Loura, L. M. S.; Silva, E. M. P. BBA Biomembranes 2024, https://doi.org/10.1016/j.bbamem.2024.184335

36) Kondacs, L.; Parijat, P.; Cobb, A. J. A.*; Kampourakis, T.* Synthesis and Biophysical Characterization of Fingolimod Derivatives as Cardiac Troponin Antagonists. ACS Med. Chem. Lett. 2024, 15, 413.

35) Lin, Q.; Lan, H.; Ma, C.; Stendall, R. T.; Shankland, K.; Musgrave, R. A.; Horton, P. N.; Baldauf, C.; Hofmann, H.-J.; Butts, C. P.; Mueller, M. M.; Cobb, A. J. A. Crystal Structure and NMR of an α,δ-Peptide Foldamer Helix Shows Side-Chains are Well Placed for Bifunctional Catalysis : Application as a Minimalist Aldolase Mimic. Angew. Chem. Int. Ed. 2023, e202305326.

34) Varandas, P. A. M. M.; Belinha, R.; Marques, S. S.; Cobb, A. J. A.; Serra, V. V.; Segundo, M. A.; Silva, E. M. P. Fluorescent head-labelled phospholipid coumarin bioconjugate as a chemical reporter for antioxidant protection in liposomes. Dyes Pigments 2023, doi.org/10.1016/j.dyepig.2023.111440

33) Bryant, L. A.; Shankland, K. S.; Straker, H. E.; Johnston, C. D.; Lees, N. R.; Cobb, A. J. A. Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols via an Intramolecular Friedel−Crafts-Type 1,4-Addition: Access to Cannabidiol Analogues. Adv. Synth. Catal. 2021, 363, 4067.

32) Parijat, P.; Kondacs, L.; Alexandrovich, A.; Gautel, M.; Cobb, A. J. A.; Kampourakis, T. High Throughput Screen Identifies Small Molecule Effectors That Modulate Thin Filament Activation in Cardiac Muscle. ACS Chem. Biol. 2021, 16, 225.

31) Townsend, D.; Shankland, K.; Weymouth-Wilson, A.; Komsta, Z.; Cobb, A. J. A. Synthesis of an intriguing steroidal constitutional isomer. 

Tetrahedron Lett., 2020, 61, 151924.

30)  Townsend, D.; Shankland, K.; Weymouth-Wilson, A.; Komsta, Z.; Evans, T.; Cobb, A. J. A. Highly Enantioselective, Organocatalytic, and Scalable Synthesis of a Rare cis,cis‐Tricyclic Diterpenoid.

Chem. Eur. J., 2020, 26, 3504.


29) Fanelli, R.; Berta, D.; Földes, T.; Rosta, E.; Atkinson, R. A.; Hofmann, H.-J.; Shankland, K.; Cobb, A. J. A. Organocatalytic Access to a cis-Cyclopentyl-γ-amino Acid: An Intriguing Model of Selectivity and Formation of a Stable 10/12-Helix from the Corresponding γ/α-Peptide.

J. Am. Chem. Soc., 2020, 132, 1382.

28) Varandas, P. A. M. M.; Cobb, A. J. A.; Segundo, M. A.; Silva, E. M. P. Emergent Glycerophospholipid Fluorescent Probes: Synthesis and Applications.

Bioconj. Chem., 2020, 31, 417.


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